β-eudesmol, a sesquiterpene from Teucrium ramosissimum , inhibits superoxide production, proliferation, adhesion and migration of human tumor cell
نویسندگان
چکیده
منابع مشابه
β-eudesmol, a sesquiterpene from Teucrium ramosissimum, inhibits superoxide production, proliferation, adhesion and migration of human tumor cell.
Reactive oxygen species are well-known mediators of various biological responses. Recently, new homologues of the catalytic subunit of NADPH oxidase have been discovered in non phagocytic cells. These new homologues (Nox1-Nox5) produce low levels of superoxides compared to the phagocytic homologue Nox2/gp91phox. In this study we examined the effect of β-eudesmol, a sesquiterpenoid alcohol isola...
متن کاملActein Inhibits Cell Proliferation and Migration in Human Osteosarcoma
BACKGROUND Osteosarcoma is one of the most common malignant bone cancers worldwide. Although the traditional chemotherapies have made some progression in the past decades, the mortality of osteosarcoma in children and adolescent is very high. Herein, the role of actein in osteosarcoma was explored. MATERIAL AND METHODS Cell viability assay was performed in osteosarcoma cell lines 143B and U2OS....
متن کاملThe type III transforming growth factor-β receptor inhibits proliferation, migration, and adhesion in human myeloma cells
Transforming growth factor-β (TGF-β) plays an important role in regulating hematopoiesis, inhibiting proliferation while stimulating differentiation when appropriate. We previously demonstrated that the type III TGF-β receptor (TβRIII, or betaglycan) serves as a novel suppressor of cancer progression in epithelial tumors; however, its role in hematologic malignancies is unknown. Here we demonst...
متن کاملMiR-125b inhibits stromal cell proliferation in giant cell tumor of bone by targeting parathyroid hormone 1 receptor
Objective(s):miR-125b has been identified as a tumor suppressor in many tumors, but its role in giant cell tumor (GCT) of bone remains poorly understood. The current study aimed to investigate the potential role and mechanism of miR-125b in GCT. Materials and Methods:Expression levels of miR-125b in GCT tissues were determined using RT-PCR. The cell proliferation was surveyed by direct cell coun...
متن کاملN-acetylcysteine inhibits proliferation, adhesion, migration and invasion of human bladder cancer cells.
OBJECTIVE Bladder cancer is not only a major public health and economically burden for the patients but also a major clinical impact for Thai urologists. The authors' aim was to study the anti-metastatic effect of N-acetylcysteine (NAC), one of the cheap, safe and widely used over-the-counter-drugs in Thailand, on the human bladder cancer cells. MATERIAL AND METHOD Effects of NAC at various c...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Environmental Toxicology and Pharmacology
سال: 2016
ISSN: 1382-6689
DOI: 10.1016/j.etap.2016.07.019